2026 Rankings

10 Best GLP-1 Weight Loss Programs of 2026

Reviewed, compared, and ranked by our editorial team. Updated March 2026.

Our team evaluated 15+ telehealth providers to bring you the top 10.

Medically reviewed content
Updated March 2026
Editorial independence
15+ providers evaluated
💡 Disclosure: GLP01 may receive compensation when you click links on this page and sign up with our partner providers. This helps fund our editorial team and keep our content free. Our rankings are based on independent research and are not influenced by compensation. Learn more.

2026 Rankings at a Glance

All 10 providers compared — click any row to jump to the full review.

Rank Provider Starting Price Rating Best For
#3 Hims & Hers Best Brand Recognition $69/mo 4.6/5 Brand Recognition Visit Site →
#4 Ro Body Best Insurance Support $45/mo* 4.5/5 Insurance Support Visit Site →
#5 Mochi Health Best for Compounded GLP-1s $79/mo 4.5/5 Compounded GLP-1s Visit Site →
#6 Found Best Holistic Approach Varies 4.4/5 Holistic Approach Visit Site →
#7 Noom Med Best Behavior Change $149/mo 4.3/5 Behavior Change Visit Site →
#8 Calibrate Best Long-Term Program Premium 4.2/5 Long-Term Program Visit Site →
#9 PlushCare Best for Existing Patients Varies 4.1/5 Existing Patients Visit Site →
#10 Henry Meds Most Flexible Plans Varies 4.0/5 Flexible Plans Visit Site →

* First month promotional pricing. "Partner" indicates an affiliate relationship.

Editor's Choice
1
Best Overall

Clinic Secret Partner

GLP-1 Weight Loss Program
4.9/5
3-Minute Approval Ships in 3 Days No Membership Fees Semaglutide & Tirzepatide

Clinic Secret takes our #1 spot for 2026 thanks to its unmatched speed and flexibility. You can get a prescription approved in as little as 3 minutes — and have medication shipped to your door within 3 days. There are no membership fees or subscriptions, making it the most straightforward option for people who want to start their GLP-1 journey without long-term commitments or hidden costs.

What makes Clinic Secret stand out is the combination of speed, medication variety, and simplicity. They offer both semaglutide and tirzepatide, giving you options based on your provider's recommendation. Their doctor-prescribed, personalized plans ensure you're getting the right medication and dosage for your specific situation. The nationwide shipping means you can access treatment regardless of where you live.

✓ Pros
  • Prescription approved in as little as 3 minutes
  • Medication shipped nationwide in 3 days or less
  • No membership or subscription fees
  • Both semaglutide and tirzepatide available
  • Doctor-prescribed, personalized plans
  • Starting at just $49/week
✕ Cons
  • Per-week pricing can add up monthly
  • Newer brand with less track record
💰
Starting at
$49/week
Visit Clinic Secret →
2
Most Affordable

Sesame Care Partner

GLP-1 Weight Loss Program
4.8/5
Most Affordable Board-Certified Providers No Insurance Needed Transparent Pricing

Sesame Care earns our #2 spot as the most affordable GLP-1 program available in 2026. With pricing starting at just $59/month on an annual plan, they offer the lowest entry point we've found — without sacrificing quality. Their board-certified providers offer both video and async consultations, and the entire process is refreshingly transparent with no hidden fees.

What sets Sesame Care apart is the combination of affordability and quality. While some competitors require insurance or charge surprise fees, Sesame Care's flat-rate model means you know exactly what you're paying from day one. Their providers take the time to understand your health history and goals before recommending a treatment plan. Prescriptions are sent directly to your pharmacy, giving you complete control.

✓ Pros
  • Starts at just $59/month with annual plan
  • Board-certified providers
  • Transparent flat-rate pricing — no hidden fees
  • Video and async consultations available
  • Prescription sent directly to your pharmacy
  • No insurance required
✕ Cons
  • Requires annual commitment for best pricing
  • Limited medication brands compared to some providers
💰
Starting at
$59/month
Visit Sesame Care →
3
Best Brand Recognition

Hims & Hers

Weight Loss Program
4.6/5
Trusted Brand Oral + Injectable FDA-Approved Novo Nordisk GLP-1s

Hims & Hers has become one of the most recognizable names in telehealth, and their weight loss program lives up to the brand's reputation. They offer oral GLP-1 kits starting at $69/month and injectable options from $199/month. As of March 2026, they now offer FDA-approved Novo Nordisk GLP-1s, giving patients access to brand-name medications through a trusted platform. Their programs include ongoing provider support and coaching for both men and women.

✓ Pros
  • Well-known, trusted brand
  • Oral and injectable GLP-1 options
  • Comprehensive program with coaching
  • Now offering FDA-approved Novo Nordisk medications
✕ Cons
  • Higher starting price for injectables ($199/mo)
  • Requires commitment upfront
💰
Oral kits starting at
$69/month
Visit Hims & Hers →
4
Best Insurance Support

Ro Body

Weight Loss Program
4.5/5
Insurance Navigation Brand-Name Meds Metabolic Labs

Ro Body stands out for patients who want help navigating insurance coverage. Their membership starts at $45 for the first month (then $145/month), but the real value is in their comprehensive care model: integrated metabolic labs, ongoing monitoring, and strong insurance navigation support. They offer Wegovy starting at $199/month on a promotional basis, making brand-name GLP-1s more accessible for those with coverage.

✓ Pros
  • Strong insurance navigation support
  • Brand-name medications available (Wegovy)
  • Integrated metabolic labs and monitoring
  • Comprehensive care approach
✕ Cons
  • Membership fee on top of medication cost
  • Higher total price than some competitors
💰
Membership starting at
$45/month*
Visit Ro Body →
5
Best for Compounded GLP-1s

Mochi Health

Weight Loss Program
4.5/5
Compounded Semaglutide $99/mo Obesity Medicine Specialists Pay-As-You-Go

Mochi Health is the go-to choice for patients specifically seeking compounded GLP-1 medications at competitive prices. For a $79/month membership, you get access to board-certified obesity medicine physicians — not just general practitioners. Compounded semaglutide runs $99/month and tirzepatide $199/month at all doses, with shipping included. Their pay-as-you-go model means no long-term contracts.

✓ Pros
  • Affordable compounded semaglutide ($99/mo)
  • Board-certified obesity medicine specialists
  • Transparent pricing, shipping included
  • Pay-as-you-go — no long-term contracts
✕ Cons
  • Membership fee ($79/mo) separate from medication
  • Compounded only — not brand-name for most meds
💰
Membership starting at
$79/month
Visit Mochi Health →
6
Best Holistic Approach

Found

Weight Care Program
4.4/5
Biology-First Approach Personalized Coaching Metabolic Optimization

Found takes a biology-first approach to weight loss, combining GLP-1 medications with personalized coaching and behavioral support. Rather than treating weight loss as a simple calorie equation, Found focuses on metabolic health optimization — addressing the underlying biology that makes losing weight difficult. Their program includes ongoing coaching and support, making it ideal for people who want a comprehensive, science-backed approach.

✓ Pros
  • Comprehensive coaching included
  • Metabolic health focus
  • Personalized approach to each patient
  • Behavioral support alongside medication
✕ Cons
  • Pricing not fully transparent upfront
  • Can be expensive with brand-name medications
💰
Pricing
Varies by plan
Visit Found →
7
Best Behavior Change

Noom Med

GLP-1 + Coaching Program
4.3/5
Psychology-Based Coaching Microdose GLP-1 Option Biomarker Monitoring

Noom is well-known for its psychology-based approach to weight loss, and Noom Med brings that expertise to GLP-1 treatment. Their microdose GLP-1 program starts at $149/month, while telehealth consultations for branded medications begin at $69/month (consult only). What makes Noom Med unique is the integration of cognitive behavioral coaching with medical treatment — helping you build sustainable habits alongside medication use. Biomarker monitoring adds another layer of personalization.

✓ Pros
  • Strong behavioral and psychological coaching
  • Coaching included in the program
  • Microdosing option for sensitive patients
  • Biomarker monitoring for personalization
✕ Cons
  • GLP-1 medication cost is often additional
  • Complex pricing tiers can be confusing
💰
Microdose program from
$149/month
Visit Noom Med →
8
Best Long-Term Program

Calibrate

Metabolic Reset Program
4.2/5
One-Year Program Metabolic Labs Included Sustainable Results Focus

Calibrate takes the long view on weight loss with their one-year metabolic reset program. This isn't a quick fix — it's a structured program combining GLP-1 medications with comprehensive lifestyle coaching, quarterly metabolic labs, and a focus on sustainable, long-term results. For patients who are serious about making lasting changes and want a guided program with accountability, Calibrate is a strong option.

✓ Pros
  • Structured year-long program with accountability
  • Quarterly metabolic labs included
  • Focus on sustainable, lasting results
  • Comprehensive lifestyle coaching
✕ Cons
  • Long commitment required (one year)
  • Premium pricing, less flexible than others
💰
Pricing
Premium (contact for details)
Visit Calibrate →
9
Best for Existing Patients

PlushCare

Telehealth + Weight Loss
4.1/5
Full-Service Telehealth Insurance Accepted Primary Care + Weight Loss

PlushCare is a full-service telehealth platform where GLP-1 consultations are available alongside primary care, mental health, and other services. If you're already a PlushCare patient — or if you want a platform where your weight management provider also has access to your broader health records — this is a convenient option. They accept insurance, which can significantly reduce costs for covered patients.

✓ Pros
  • Full-service telehealth platform
  • Insurance accepted for many plans
  • Existing patient records accessible
  • Primary care + weight management in one place
✕ Cons
  • Not specialized in weight loss
  • GLP-1 is just one of many services offered
💰
Pricing
Varies (insurance accepted)
Visit PlushCare →
10
Most Flexible Plans

Henry Meds

Compounded GLP-1 Program
4.0/5
Month-to-Month No Contracts Ships to All 50 States

Henry Meds rounds out our top 10 with the most flexible subscription model we've seen. They offer compounded semaglutide and tirzepatide on a month-to-month basis with no long-term commitments or contracts. Cancel anytime. They ship to all 50 states, making them accessible nationwide. If you're looking to try GLP-1 treatment without being locked into a lengthy commitment, Henry Meds is worth considering.

✓ Pros
  • Flexible month-to-month subscription
  • Competitive compounded pricing
  • No contracts — cancel anytime
  • Ships to all 50 states
✕ Cons
  • Compounded medications only
  • Less established brand
  • Limited coaching or support compared to others
💰
Pricing
Varies (no contracts)
Visit Henry Meds →

Full Side-by-Side Comparison

All 10 providers compared across key criteria.

Rank Provider Starting Price Approval Time Medications Insurance Coaching Rating
#1 Sesame Care $59/mo Same day GLP-1 medications Not required Video + async 4.9
#2 Clinic Secret $49/wk ~3 minutes Semaglutide, tirzepatide Not required Provider support 4.7
#3 Hims & Hers $69/mo (oral) 1–2 days Oral + injectable, Novo Nordisk Not required Coaching included 4.6
#4 Ro Body $45/mo* 1–3 days Wegovy, brand-name Navigation support Monitoring included 4.5
#5 Mochi Health $79/mo + med 1–2 days Compounded semaglutide, tirzepatide Not required Specialist physicians 4.5
#6 Found Varies 1–3 days Multiple GLP-1 options Varies Coaching + behavioral 4.4
#7 Noom Med $149/mo 1–3 days Microdose + branded Not required Psychology-based 4.3
#8 Calibrate Premium 1–5 days GLP-1 + lifestyle Some support Year-long coaching 4.2
#9 PlushCare Varies 1–2 days GLP-1 consultations Accepted Primary care 4.1
#10 Henry Meds Varies 1–3 days Compounded semaglutide, tirzepatide Not required Limited 4.0

* First month promotional pricing. Medication costs may be additional for some providers.

How We Evaluated These Providers

Our editorial team spent over 100 hours researching, testing, and comparing GLP-1 telehealth providers. We evaluated each platform across eight key criteria to create rankings that genuinely help patients find the right fit.

💰
Pricing & Value

Total cost of treatment including consultation fees, medication, membership fees, and hidden charges. We calculated the true monthly cost for each provider.

🩺
Provider Credentials

We verified that providers are board-certified and evaluated the quality and thoroughness of medical consultations offered.

💊
Medication Options

Range of GLP-1 medications available, including branded vs. compounded, semaglutide vs. tirzepatide, and dosage flexibility.

Speed of Approval

How quickly patients can go from initial consultation to receiving their medication — from minutes to days.

📱
User Experience

Platform usability, sign-up process, mobile app quality, and overall patient journey from start to treatment.

📞
Customer Support

Responsiveness, availability, and helpfulness of customer service channels when patients need assistance.

🏥
Insurance Support

Whether insurance is accepted or required, and the quality of insurance navigation assistance provided.

🔒
Transparency

Clear, honest pricing without hidden fees. Straightforward terms of service and realistic marketing claims.

What Are GLP-1 Medications?

GLP-1 (glucagon-like peptide-1) receptor agonists are a class of prescription medications originally developed to treat type 2 diabetes. They work by mimicking a natural hormone that helps regulate blood sugar, slow gastric emptying, and reduce appetite — leading to significant weight loss in many patients.

In recent years, several GLP-1 medications have been FDA-approved specifically for weight management, including semaglutide (branded as Wegovy) and tirzepatide (branded as Zepbound). Clinical trials have shown average weight loss of 15–20% of body weight over 68 weeks, making these some of the most effective weight loss medications available.

Today, multiple telehealth platforms offer access to GLP-1 medications through online consultations with licensed providers, making them more accessible than ever. However, not all programs are created equal — which is why we created this guide.

Understanding Your Options: Branded vs. Compounded

When exploring GLP-1 medications online, you'll likely encounter two categories: branded medications and compounded medications. Understanding the difference is important for making an informed decision.

Branded Medications

These are the FDA-approved, name-brand drugs manufactured by pharmaceutical companies like Novo Nordisk (Ozempic, Wegovy) and Eli Lilly (Mounjaro, Zepbound). They undergo rigorous clinical trials and quality controls. However, they tend to be more expensive and may require insurance coverage.

Compounded Medications

Compounded GLP-1 medications are custom-prepared by licensed compounding pharmacies. They contain the same active ingredients (like semaglutide) but are typically available at lower prices. Many telehealth platforms offer compounded versions as a more affordable alternative. These medications are prepared under FDA oversight but are not individually FDA-approved products.

Cost & Insurance: Finding the Best Value

The cost of GLP-1 medications can vary dramatically. Brand-name medications like Wegovy can cost $1,000+ per month without insurance, while telehealth platforms offering compounded versions can bring costs down to $59–$300 per month.

Most of the telehealth providers in our rankings do not require insurance, which actually simplifies the process. You'll know your exact cost upfront, with no surprise bills from insurance claims or prior authorization delays. For many people, this transparent pricing model is more practical and affordable than navigating the traditional insurance route.

If you do have insurance that covers GLP-1 medications, providers like Ro Body and PlushCare offer strong insurance navigation support. But for the majority of people exploring their options, the telehealth programs we review offer the clearest path to getting started.

Are GLP-1 Medications Right for You?

GLP-1 medications are generally prescribed for adults with a BMI of 30 or higher (obesity), or a BMI of 27+ with at least one weight-related health condition such as type 2 diabetes, high blood pressure, or high cholesterol.

These medications work best as part of a comprehensive approach that includes dietary changes and increased physical activity. They are not a "magic pill" — but for eligible patients, they can be a powerful tool for achieving and maintaining meaningful weight loss.

The best way to determine if GLP-1 medications are right for you is to consult with a licensed healthcare provider. Many of the telehealth platforms in our rankings offer free or low-cost initial consultations to help you understand your options.

📋
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FAQ

Frequently Asked Questions

Common questions about GLP-1 medications and our reviewed providers.

Based on our research, Sesame Care offers the most affordable option at $59/month with an annual plan. This is significantly less than brand-name medications, which can cost $1,000+ per month without insurance. Other telehealth providers in our top 10 range from $69/month (Hims & Hers oral kits) to premium pricing at Calibrate.
No. Most providers in our top 10 — including Clinic Secret (#1) and Sesame Care (#2) — do not require insurance. You pay a flat rate directly. However, if you do have insurance, providers like Ro Body (#4) and PlushCare (#9) offer strong insurance support that can significantly reduce costs.
It depends on the provider. Clinic Secret offers the fastest approval — as little as 3 minutes — with medication shipped in 3 days. Sesame Care typically processes consultations the same day. Most providers in our top 10 can have you approved within 1–3 days, with medication arriving within a week.
GLP-1 receptor agonists have been extensively studied in clinical trials involving tens of thousands of participants. FDA-approved versions like semaglutide and tirzepatide have well-established safety profiles. Common side effects include nausea, which typically improves over time. As with any medication, it's important to discuss your personal health history with a licensed provider before starting treatment.
Semaglutide (found in Ozempic and Wegovy) targets the GLP-1 receptor, while tirzepatide (found in Mounjaro and Zepbound) targets both GLP-1 and GIP receptors. Clinical trials have shown that tirzepatide may produce slightly greater weight loss on average, but both are highly effective. Providers like Clinic Secret and Mochi Health offer both options.
It depends on your priorities. Branded medications (like Wegovy and Zepbound) are FDA-approved products with extensive clinical data, but they're significantly more expensive. Compounded versions contain the same active ingredients at lower prices but are not individually FDA-approved. Providers like Hims & Hers and Ro Body offer branded options, while Mochi Health and Henry Meds specialize in compounded versions.
In many cases, yes. GLP-1 medications prescribed for weight management or diabetes are typically eligible for HSA (Health Savings Account) and FSA (Flexible Spending Account) reimbursement. Check with your specific plan administrator to confirm eligibility for the telehealth program you choose.
Results vary by individual, but clinical trials of GLP-1 medications have shown average weight loss of 15–20% of body weight over 68 weeks. For someone weighing 200 lbs, that could mean losing 30–40 lbs. Results depend on factors including dosage, diet, exercise, and individual metabolism. These medications are most effective when combined with lifestyle changes — which is why programs with coaching (like Found, Noom Med, and Calibrate) can be particularly effective.
No. All 10 providers in our rankings offer fully online consultations with licensed healthcare providers. You can complete the entire process — from initial consultation to prescription — from your phone or computer. Some providers offer video consultations, while others use asynchronous (text-based) evaluations.
Most providers in our top 10 allow you to cancel or switch without major penalties. Providers like Henry Meds and Clinic Secret are especially flexible with month-to-month or per-order pricing. However, programs like Calibrate require a year-long commitment, so it's worth considering your flexibility needs before signing up. We recommend starting with a provider that offers low-commitment options if you're unsure.

Our Top Picks for 2026

After reviewing 15+ providers, these are the two we recommend most. Both offer affordable, transparent GLP-1 programs with licensed providers.

Affiliate Disclosure: GLP01 is an independent educational resource. Some links on this page are affiliate links, meaning we may receive a commission if you sign up through our links — at no extra cost to you. Specifically, our links to Clinic Secret (#1) and Sesame Care (#2) are affiliate partnerships. Links to all other providers (#3–#10) are standard, non-affiliate links. This compensation helps us maintain our website and continue producing free, high-quality content. Our editorial team independently evaluates providers and compensation does not influence our rankings or reviews.
Medical Disclaimer: The information on this page is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting any medication, including GLP-1 receptor agonists. GLP01 is not a healthcare provider and does not prescribe medications. Telehealth consultations are conducted by independent licensed providers.
Results Disclaimer: Individual results vary. Weight loss outcomes depend on many factors including starting weight, medication dosage, diet, exercise, and individual metabolism. The weight loss figures cited on this page are based on clinical trial averages and may not reflect your personal experience. GLP-1 medications are prescription drugs that should only be used under medical supervision.
Editorial Note: Our rankings are updated regularly as providers change their offerings, pricing, and services. Last updated March 31, 2026. Provider information, pricing, and availability are subject to change. We encourage readers to verify current details directly with each provider before making a decision.